Picture of Shelley Kirychuk

Shelley Kirychuk BScN, MSc, MBA, PhD Associate Professor

Address
104 Clinic Place, P.O. Box 23, Saskatoon, SK, S7N 2Z4

Education

  • BScN University of Saskatchewan, Canada.
  • MSC in Preventive Medicine and Environmental Health (emphasis in Industrial Hygiene) from the University of Iowa. Thesis "Oil/Water Sprinkling Intervention in a Swine Confinement Unit" (K. Donham - Advisor).
  • MBA from University of Saskatchewan.
  • PhD in interdisciplinary studies (emphasis on Occupational Hygiene) from the University of Saskatchewan joint with Colorado State University. Thesis: “Particulate distribution and relationship to endotoxin in poultry operations” (S. Reynolds and N. Koehncke - Advisors)

Professional Roles and Areas of Interest

  • Associate Professor, Department of Medicine, College of Medicine, Canadian Centre for Health and Safety in Agriculture.
  • Associate member of the School of Public Health, College of Nursing and Community Health and Epidemiology.
  • Co-PI and Director of the CIHR-STIHR Public Health and the Agricultural Rural Ecosystem Training Program (PHARE)
  • Leads the National Agricultural Industrial Hygiene Laboratory
  • Epidemiology of rural and agricultural related exposures and respiratory health outcomes

Current Research

Period

Project

Applicants & Investigators

Funding Sources

2020/02 – 2024/03

Titre de la demande: Antimicrobial resistance genes in bioaerosols in Canadian arctic, rural, and urban environments: sources, profiles, transport and fate

Principal Applicant: Caroline Duchaine

Co-applicant: Shelley Kirychuk, Allison McGeer, Brenda Coleman, Ed Topp, Jacques Corbeil, Marie-Lou Gaucher, Michel Bergeron, Scott McEwen, Thierry Badard, Stephane Goodbout

Collaborator: Anne-Marie Delort, Maosheng Yao, Maurice Boissinot, Patrick. O'Shaughnessy, Pierre Amato, Richard Reid-Smith;

NSERC Discovery Frontiers – 4,038,500

2020/01 – 2021/04

Effects of low elevations CO2 on lung Infection and inflammation

Principal Applicant: Shelley Kirychuk

Co-applicant: David Schneberger and Carey Simonson

Respiratory Research Centre Team Building Grant - 24,918

2020/01 – 2021/04

One of these things is not like the other: Unraveling the sex differential inflammatory response to airborne agricultural exposures

Principal Applicant: Shelley Kirychuk

Co-applicant: David Schneberger

Collaborators: Todd Wyatt, Baljit Singh, Gurpreet Aulakh

University of Saskatchewan, ComRAD Program, total Funding

- 29,870

2020/01 – 2022/01

The Anti-Inflammatory potential of Nature Immuno on Inflammation induced by LPS

Prinicipal Applicant: Shelley Kirychuk and Amanda Nascimento

MITACS Elevate – 60,000

2018/12 – 2019/07

The effects of Resp-Aid on Asthma

Principal Applicant: Shelley Kirychuk and Amanda Nascimento

MITACS Accelerate – 30,000

2018/03 – 2020/02

Mould as a respiratory risk factor for rural populations

Principal Applicant: Shelley Kirychuk

Co-applicant: Joshua Lawson, Vivian Ramsden, George Katselis

SHRF Collaborative Innovation Development Grant – 50,000

2018/06 – 2019/12

Air Quality and Respiratory Health in Saskatchewan: the influence of PM2.5

Principal Applicant: Shelley Kirychuk

Co-applicant: John Gordon, Joshua Lawson, Donna Rennie, Chandima Karunanayake, Niels Koehncke

SHRF Ideas that Inspire Grant – 25,000

2017/12 – 2021/05

Dust Removal and Microbial Deactivation for Improving Air Quality in Livestock Barns

Principal Applicant: Lifeng Zhang

Co-applicant: Shelley Kirychuk, Huiqing Guo, Bernardo Predicala, Myra Martel

Ministry of Agriculture, Agricultural Development Fund – 189,000

2017/05 – 2019/05

Unravelling Respiratory Inflammation from Co-exposures in Agricultural Production

Principal Applicant: Shelley Kirychuk

Office of the Vice-President Research, President’s NSERC – 10,000

2017/03 – 2018/02

Mamawohkamatowin (Working Together) - Enhancing Health & Wellness

Principal Applicant: Vivian Ramsden

Co-applicant: Shelley Kirychuk, Sylvia Abonyi, James Dosman, Mark Fenton, Holly Graham-Marrs, Chandima Karunanayake

CIHR Catalyst Grant – 150,000

2017/03 – 2018/08

Dust Exposure Reduction for Workers: Airborne Dust Removal in Poultry Houses by Electrostatic Space Charge System (ESCS)

Principal Applicant: Lifeng Zhang

Co-applicant: Huiqing Guo, Shelley Kirychuk,

SHRF Collaborative Innovation Development Grant – 47,000

2016/12 – 2021/12

Research Opportunities Presented by the Beef Cattle Research a Teaching Unit

Principal Applicant: Terry Fonstad, Richard Farrell

Co-applicant: J Diane Knight, Jeff Schoenau, Huiqing Guo, Shelley Kirychuk

Ministry of Agriculture, Agricultural Development Fund – 418,000

2014/12 - 2019/12

Canadian Agrisafety Applied Research Program

Principal Applicant: James Dosman; Co-investigator : Caroline Duchaine; James Wasserman; Shelley Kirychuk; Co-applicant : Bernardo Predicala; Stephane Lemay;

Agriculture and Agri-Food Canada Agro innovation Industry-led R and D; Total Funding - 1,080,216;

Portion of Funding Received – 996,552

2016/6 - 2017/10

Effect of low dose carbon dioxide and ammonia on barn dust induced lung inflammation

Principal Applicant: Shelley Kirychuk Co-investigator: David Schneberger

University of Saskatchewan, ComRAD Program, total Funding - 21,489

2015/5 - 2017/5

Barn Dust Exposure and Lung Inflammation in Animals and Workers - the role of lung surfactant

Principal Applicant: Shelley Kirychuk; Co-applicant: Baljit Singh; Joyce Wilson; Co-investigator: David Scheberger

University of Saskatchewan One Health Development

Program, total Funding - 20,000

2011/10 - 2016/9

Assess, Redress, Re-assess: Addressing Disparities in Respiratory Health Among First Nations People

Co-investigator : Shelley Kirychuk; Principal Investigator : Dosman J, Abonyi S, Episkenew, J, and Pahwa P

Canadian Institutes of Health Research (CIHR) Operating Grant, total Funding - 1,592,521

2015/5 - 2016/5

An Investigation of personal exposure monitoring and environmental exposures in

relation to rural areas and asthma among children

Co-applicant : George Katselis; Shelley Kirychuk; Co-investigator : Donna Rennie; Principal Applicant : Joshua Lawson

Saskatchewan Health Research Foundation (SHRF), CID program, total Funding - 80,000

2014/7 - 2015/6

Reducing Pathogen Distribution from Animal Transportation

Co-applicant : Shelley Kirychuk; Trevor Crowe; Principal Applicant : Bernardo Predicala

Saskatchewan Ministry of Agriculture; Agriculture Development Fund, total Funding 142,208

Published Papers

  • Rennie D, Karunanayake CP, Lawson JA, Kirychuk S, McMullin K, Abonyi S, Seeseequasis J, MacDonald J, Dosman JA, Pahwa P. (2020). Domestic risk factors for atopic and non-atopic asthma in Canadian First Nations children. Children, 7(5): 38.
  • Nascimento AF, Thompson B, Rocha PRD, Kirychuk S, Bernardi MM, Felicio LF. (2020). Hyperprolactinemia Impaired the Effects of Lipopolysaccharide on Both Body Temperature and Sickness Behavior in Virgin Female Rats. Neuroimmunomodulation, 26: 285-291.
  • Dankwah E, Zeng W, Feng C, Kirychuk S, Farag M. (2019). The Social determinants of Health Facility Delivery Among Reproductive Aged Women in Ghana. Reproductive Health, 16(1): 101
  • Murabecka S, Groulx N, Savory E, Cutts T, Theriault S, Scott J, Roy C, Turgeon
  • N, Bryce E, Astrakianakis G, Kirychuk S, Girard M, Kobinger G, Zhang C, Duchaine C. (2019). Bioaerosols and transmission, a diverse and growing community of practice. Frontiers in Public Health, 7: 23-29.
  • Dosman J, Karunanayake C, McMullin K, Abonyi S, Rennie D, Lawson J, Kirychuk S, Koehncke N, Seeseequasis J, Jimmy L, Ramsden V, Fenton M, Marchildon G, King M, Pahwa P. (2019). Risk Factors for Snoring in Two Canadian First Nations Communities. Clocks & Sleep, 1(1): 117-125.
  • Schneberger D, DeVasure JM, Kirychuk SP, & Wyatt TA. (2018). Organic barn dust inhibits surfactant protein D production through protein kinase-c alpha dependent increase of GPR116. PLOS One, 13(12)
  • Karunanayake C, Dosman J, Rennie D, Lawson J, Kirychuk S, Fenton M, Ramsden V, Seeseequasis J, Abonyi S, Pahwa P. (2018). Incidence of daytime sleepiness an associated factors in two First Nations communities in Saskatchewan, Canada. Clocks & Sleep, 1(1): 13-25
  • Nascimento A, Kirychuk S, Bernardi M, Felicio L. (2018). Zinc alleviates LPS interference with both body temperature and sickness behavior in virgin female rats. Neuroimmunomodulation, 25(1): 1-7.
  • Oluwole O, Rennie D, Senthilselvan A, Dyck R, Afanasieva A, Kirychuk S, Katselis G, Lawson J. (2018). The association between endotoxin in house dust with atopy and exercise-induced bronchospasm in children with asthma. Environmental Research, 164: 302-309.
  • Oluwole O, Rennie D, Senthilselvan A, Dyck R, Afanasieva A, Kirychuk S, Katselis G, Lawson J. (2018). The association between endotoxin and beta-(1 - 3)-D glucan in house dust with asthma severity among schoolchildren. Respiratory Medicine, 138: 38-46.
  • Kajiwara-Morita A, Karunanayake C, Dosman J, Lawson J, Kirychuk S, Rennie D, Dyck R, Koehncke N, Senthilselvan A, Paha P, & Saskatchewan, Rural Health Study Research Team. (2018). Prevalence and Determinants of Sinus Problems in Farm and Non-Farm Populations of Rural Saskatchewan, Canada. Sinusitis, 3(1): 1-19.
  • Pahwa P, Rana M, Pickett W, Karunanayake C, Amin K, Koehncke N, Elliot V, Hagel L, Lawson J, Rennie D, Kirychuk S, Janzen B, Dyck R, Dosman J. (2018). Correction to: Cohort profile: the Saskatchewan Rural Health Study—adult component. BMC Research Notes, 11(1): 191.
  • Van der Spuy I, Karunanayake C, Dosman J, McMullin K, Zhao G, Abonyi S, Rennie D, Lawson J, Kirychuk S, Macdonald J, Jimmy L, Koehncke N, Ramsden V, Fenton M, Marchildon G, King M, Pahwa P. (2017). Determinants of excessive daytime sleepiness in two First Nation communities. BMC Pulmonary Medicine, 17(1): 192-200.
  • Pahwa P, Rana M, Pickett W, Karunanayake C, Amin K, Rennie D, Lawson J, Kircyhuk S, Janzen B, Koehncke N, Dosman J. (2017). Cohort profile: the Saskatchewan Rural Health Study--adult component. BMC Research Notes, 10(1): 732-738.
  • Karunanayake C, Rennie D, Ramsden V, Fenton M, Kirychuk S, Lawson J, Henderson R, Jimmy L, Seeseequasis J, Abonyi S, Dosman J, Pahwa P, & The First Nations Lung Health Project Research Team. (2017). Bronchitis and Its Associated Risk Factors in First Nations Children. Children, 4(12): 103
  • Katapally T, Abonyi S, Episkenew J, Ramsden V, Karunanayake C, Kirychuk S, Rennie D, Dosman J, Pahwa P. (2017). Catalyzing Action on First Nations Respiratory Health Using Community-based Participatory Research: Integrated Knowledge Translation through Strategic Symposia. Engaged Scholar Journal: Community-Engaged Research, Teaching, and Learning, 2(1): 59-70.
  • Schneberger D., DeVasure J.M., Bailey K.L., Romberger D.J., Wyatt T.A. (2016) Effects of low- level CO2 on innate immune response to organic dust from swine confinement barns. J. Occup. Med. Toxicol. Mar 24;12:9. Doi: 10.1186/s12995-017-0155-8
  • Schneberger D., Aulakh G., Channabasappa S., Singh B. (2016) Toll-like receptor 9 partially regulates lung inflammation induced following exposure to chicken barn air. J. Occup. Med. Toxicol. Jul 1;11:31. doi: 10.1186/s12995-016-0121-x
  • Rennie D, *Oluwole O, Kirychuk S, Lawson J, Karunanayake C, Cockroft D, Willson P. (2016). Indoor mold exposure and current asthma among school-aged children in Saskatchewan, Canada.Indoor Air. Epub apr 24: 1-9.
  • O'Connor AM, Auvermann BW, Higgins JP, Kirychuk SP, Sargeant JM, Von Essen SG, Glanville JM, Wood H. (2016). Updated systematic review: associations between proximity to animal feeding operations and health of individuals in nearby communities. Environmental Health Perspectives. Submitted
  • Janzen B, Karunanayake C, Rennie D, Pickett W, Lawson J, Kirychuk S, Hagel L, Senthilselvan A, Koehncke N, Dosman J, Pahwa P.(2016). Gender Differences in the Association of Individual and Contextual Exposures with Lung Function in a Rural Canadian Population. Lung.

Accepted

  • Schneberger D., Cloonan D., DeVasure J.M., Bailey K.L., Romberger D.J., Wyatt T.A. (2015) Effect of elevated carbon dioxide on bronchial epithelial innate immune receptor response to organic swine confinement barns. Int. Immunopharmacol. 27(1):76-84.
  • Schneberger D., Gordon J.R., Heires A.J., DeVasure J.D., Boten J.A., Romberger D.J., Wyatt
  • T.A. (2015) CXCL8(3-74)K11R/G31P blocks lung inflammation in swine barn dust-instilled mice. Pulm. Pharmacol. Ther. 31:55-62.
  • Dosman JA, Hagel L, King N, Koehncke N, Kirychuk S, Trask C, Neudorf J, Day L, Volklander D, Pickett W. (2015). The hierarchy of control in the epidemic of farm injury. Journal of agromedicine. 20(3): 360-369.
  • Guarrasi Justene*,Trask Catherine, and Kirychuk Shelley. (2015). A Systematic Review of Occupational Exposure to Hydrogen Sulfide in Livestock Operations. Journal of agromedicine. 20(2): 225--236.
  • Punam Pahwa, Sylvia Abonyi, Chandima Karunanayake, Donna Rennie, Bonnie Janzen, Shelley Kirychuk, Josh Lawson, Tarun Katapally, Kathleen MaMullin, Jeremy Seeseequasis, Arnold Naytowhow, Louise Hagel, Roland Dyck, Mark Fenton, Ambikaipakan Senthilselvan, Vivian Ramsden, Malcolm King, Niels Koehncke, Greg Marchildon, Lesley McBain, Thomas Smith Windsor, Janet Smylie, Jo-Ann Episkenew and James A. Dosman. (2015). A community- based participatory research methodology to assess, Redress, and Re-assess Disparities in Respiratory Health Among First Nations People. BioMed Central Research Notes. 8(1): 199.